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Sodium-Hydrogen Exchanger Isoform-1 Inhibition: A Promising Pharmacological Intervention for Resuscitation from Cardiac Arrest

Out-of-hospital sudden cardiac arrest is a major public health problem with an overall survival of less than 5%. Upon cardiac arrest, cessation of coronary blood flow rapidly leads to intense myocardial ischemia and activation of the sarcolemmal Na(+)-H(+) exchanger isoform-1 (NHE-1). NHE-1 activati...

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Detalles Bibliográficos
Autores principales:	Gazmuri, Raúl J., Radhakrishnan, Jeejabai, Ayoub, Iyad M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538998/ https://www.ncbi.nlm.nih.gov/pubmed/31067690 http://dx.doi.org/10.3390/molecules24091765

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