In-Cell Synthesis of Bioorthogonal Alkene Tag S-Allyl-Homocysteine and Its Coupling with Reprogrammed Translation

In this study, we report our initial results on in situ biosynthesis of S-allyl-l-homocysteine (Sahc) by simple metabolic conversion of allyl mercaptan in Escherichia coli, which served as the host organism endowed with a direct sulfhydration pathway. The intracellular synthesis we describe in this...

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Detalles Bibliográficos
Autores principales: Nojoumi, Saba, Ma, Ying, Schwagerus, Sergej, Hackenberger, Christian P. R., Budisa, Nediljko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539321/
https://www.ncbi.nlm.nih.gov/pubmed/31075919
http://dx.doi.org/10.3390/ijms20092299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539321/
https://www.ncbi.nlm.nih.gov/pubmed/31075919
http://dx.doi.org/10.3390/ijms20092299

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