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Earliest Mechanisms of Dopaminergic Neurons Sufferance in a Novel Slow Progressing Ex Vivo Model of Parkinson Disease in Rat Organotypic Cultures of Substantia Nigra

The current treatments of Parkinson disease (PD) are ineffective mainly due to the poor understanding of the early events causing the decline of dopaminergic neurons (DOPAn). To overcome this problem, slow progressively degenerating models of PD allowing the study of the pre-clinical phase are cruci...

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Detalles Bibliográficos
Autores principales: Dal Ben, Matteo, Bongiovanni, Rosario, Tuniz, Simone, Fioriti, Emanuela, Tiribelli, Claudio, Moretti, Rita, Gazzin, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539377/
https://www.ncbi.nlm.nih.gov/pubmed/31064126
http://dx.doi.org/10.3390/ijms20092224