An Oncolytic Adenovirus Vector Expressing p14 FAST Protein Induces Widespread Syncytium Formation and Reduces Tumor Growth Rate In Vivo

Intratumoral injection of oncolytic viruses provides a direct means of tumor cell destruction for inoperable tumors. Unfortunately, oncolytic vectors based on human adenovirus (HAdV) typically do not spread efficiently throughout the tumor mass, reducing the efficacy of treatment. In this study, we...

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Detalles Bibliográficos
Autores principales: Del Papa, Josh, Petryk, Julia, Bell, John C., Parks, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539411/
https://www.ncbi.nlm.nih.gov/pubmed/31193718
http://dx.doi.org/10.1016/j.omto.2019.05.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539411/
https://www.ncbi.nlm.nih.gov/pubmed/31193718
http://dx.doi.org/10.1016/j.omto.2019.05.001

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