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miR-133b Downregulation Reduces Vulnerable Plaque Formation in Mice with AS through Inhibiting Macrophage Immune Responses

Atherosclerosis (AS) is a chronic inflammatory disease characterized by accumulating deposition of lipids in the arterial intima. Notably, macrophages participate centrally in the pathogenesis of this deadly disease. In this study, we established AS mouse models in order to investigate the effect of...

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Detalles Bibliográficos
Autores principales: Zheng, Cheng-Gen, Chen, Bing-Yu, Sun, Ren-Hua, Mou, Xiao-Zhou, Han, Fang, Li, Qian, Huang, Hai-Jun, Liu, Jing-Quan, Tu, Yue-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539412/
https://www.ncbi.nlm.nih.gov/pubmed/31146256
http://dx.doi.org/10.1016/j.omtn.2019.04.024