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Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies

Neoplastic epithelial cells coexist in carcinomas with various non-neoplastic stromal cells, together creating the tumor microenvironment. There is a growing interest in the cross-talk between tumor cells and stromal fibroblasts referred to as carcinoma-associated fibroblasts (CAFs), which are frequ...

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Detalles Bibliográficos
Autores principales: Yoshida, Go J., Azuma, Arata, Miura, Yukiko, Orimo, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539414/
https://www.ncbi.nlm.nih.gov/pubmed/31067787
http://dx.doi.org/10.3390/ijms20092256