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Modulating Heterologous Pathways and Optimizing Culture Conditions for Biosynthesis of trans-10, cis-12 Conjugated Linoleic Acid in Yarrowia lipolytica

A novel recombinant strain has been constructed for converting glycerol into a specific conjugated linoleic acid isomer (trans-10, cis-12 CLA) using Yarrowia lipolytica as host. The lipid accumulation pathway was modified for increasing lipid content. Overexpression of the diacylglycerol transferase...

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Detalles Bibliográficos
Autores principales: Wang, Xun, Xia, Qianjun, Wang, Fei, Zhang, Yu, Li, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539415/
https://www.ncbi.nlm.nih.gov/pubmed/31064128
http://dx.doi.org/10.3390/molecules24091753