HDAC5 Expression in Urothelial Carcinoma Cell Lines Inhibits Long-Term Proliferation but Can Promote Epithelial-to-Mesenchymal Transition

Class I histone deacetylases (HDACs) generally promote cell proliferation and tumorigenesis, whereas class IIA HDACs like HDAC4 and HDAC5 may promote or impede cancer development in a tissue-dependent manner. In urothelial carcinoma (UC), HDAC5 is often downregulated. Accordingly, HDAC5 was weakly e...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaguva Vasudevan, Ananda Ayyappan, Hoffmann, Michèle J., Beck, Michael L. C., Poschmann, Gereon, Petzsch, Patrick, Wiek, Constanze, Stühler, Kai, Köhrer, Karl, Schulz, Wolfgang A., Niegisch, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539474/
https://www.ncbi.nlm.nih.gov/pubmed/31052182
http://dx.doi.org/10.3390/ijms20092135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539474/
https://www.ncbi.nlm.nih.gov/pubmed/31052182
http://dx.doi.org/10.3390/ijms20092135

Ejemplares similares