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Single-Cell RNA-Sequencing Identifies Activation of TP53 and STAT1 Pathways in Human T Lymphocyte Subpopulations in Response to Ex Vivo Radiation Exposure

Detrimental health consequences from exposure to space radiation are a major concern for long-duration human exploration missions to the Moon or Mars. Cellular responses to radiation are expected to be heterogeneous for space radiation exposure, where only high-energy protons and other particles tra...

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Detalles Bibliográficos
Autores principales: Moreno-Villanueva, Maria, Zhang, Ye, Feiveson, Alan, Mistretta, Brandon, Pan, Yinghong, Chatterjee, Sujash, Wu, Winston, Clanton, Ryan, Nelman-Gonzalez, Mayra, Krieger, Stephanie, Gunaratne, Preethi, Crucian, Brian, Wu, Honglu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539494/
https://www.ncbi.nlm.nih.gov/pubmed/31083348
http://dx.doi.org/10.3390/ijms20092316