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The Physics of Entropic Pulling: A Novel Model for the Hsp70 Motor Mechanism

Hsp70s use ATP to generate forces that disassemble protein complexes and aggregates, and that translocate proteins into organelles. Entropic pulling has been proposed as a novel mechanism, distinct from the more familiar power-stroke and Brownian ratchet models, for how Hsp70s generate these forces....

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Detalles Bibliográficos
Autores principales: Sousa, Rui, Lafer, Eileen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539501/
https://www.ncbi.nlm.nih.gov/pubmed/31083504
http://dx.doi.org/10.3390/ijms20092334