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The Physics of Entropic Pulling: A Novel Model for the Hsp70 Motor Mechanism
Hsp70s use ATP to generate forces that disassemble protein complexes and aggregates, and that translocate proteins into organelles. Entropic pulling has been proposed as a novel mechanism, distinct from the more familiar power-stroke and Brownian ratchet models, for how Hsp70s generate these forces....
Autores principales: | Sousa, Rui, Lafer, Eileen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539501/ https://www.ncbi.nlm.nih.gov/pubmed/31083504 http://dx.doi.org/10.3390/ijms20092334 |
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