Cholesterol-Lowering Gene Therapy Prevents Heart Failure with Preserved Ejection Fraction in Obese Type 2 Diabetic Mice

Hypercholesterolemia may be causally related to heart failure with preserved ejection fraction (HFpEF). We aimed to establish a HFpEF model associated with hypercholesterolemia and type 2 diabetes mellitus by feeding a high-sucrose/high-fat (HSHF) diet to C57BL/6J low-density lipoprotein receptor (L...

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Detalles Bibliográficos
Autores principales: Aboumsallem, Joseph Pierre, Muthuramu, Ilayaraja, Mishra, Mudit, De Geest, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539537/
https://www.ncbi.nlm.nih.gov/pubmed/31064116
http://dx.doi.org/10.3390/ijms20092222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539537/
https://www.ncbi.nlm.nih.gov/pubmed/31064116
http://dx.doi.org/10.3390/ijms20092222

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