Pyrimidine 2,4-Diones in the Design of New HIV RT Inhibitors

The pyrimidine nucleus is a versatile core in the development of antiretroviral agents. On this basis, a series of pyrimidine-2,4-diones linked to an isoxazolidine nucleus have been synthesized and tested as nucleoside analogs, endowed with potential anti-HIV (human immunodeficiency virus) activity....

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Detalles Bibliográficos
Autores principales: Romeo, Roberto, Iannazzo, Daniela, Veltri, Lucia, Gabriele, Bartolo, Macchi, Beatrice, Frezza, Caterina, Marino-Merlo, Francesca, Giofrè, Salvatore V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539630/
https://www.ncbi.nlm.nih.gov/pubmed/31052607
http://dx.doi.org/10.3390/molecules24091718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539630/
https://www.ncbi.nlm.nih.gov/pubmed/31052607
http://dx.doi.org/10.3390/molecules24091718

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