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The polypeptide GALNT6 Displays Redundant Functions upon Suppression of its Closest Homolog GALNT3 in Mediating Aberrant O-Glycosylation, Associated with Ovarian Cancer Progression

Epithelial ovarian cancer (EOC) represents the most lethal gynecologic malignancy; a better understanding of the molecular mechanisms associated with EOC etiology could substantially improve EOC management. Aberrant O-glycosylation in cancer is attributed to alteration of N-acetylgalactosaminyltrans...

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Detalles Bibliográficos
Autores principales: Sheta, Razan, Bachvarova, Magdalena, Macdonald, Elizabeth, Gobeil, Stephane, Vanderhyden, Barbara, Bachvarov, Dimcho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539655/
https://www.ncbi.nlm.nih.gov/pubmed/31071912
http://dx.doi.org/10.3390/ijms20092264