A Natural mtDNA Polymorphism in Complex III Is a Modifier of Healthspan in Mice

In this study, we provide experimental evidence that a maternally inherited polymorphism in the mitochondrial cytochrome b gene (mt-Cytb; m.15124A>G, Ile-Val) in mitochondrial complex III resulted in middle-aged obesity and higher susceptibility to diet-induced obesity, as well as age-related inf...

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Detalles Bibliográficos
Autores principales: Hirose, Misa, Künstner, Axel, Schilf, Paul, Tietjen, Anna Katharina, Jöhren, Olaf, Huebbe, Patricia, Rimbach, Gerald, Rupp, Jan, Schwaninger, Markus, Busch, Hauke, Ibrahim, Saleh M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539666/
https://www.ncbi.nlm.nih.gov/pubmed/31085998
http://dx.doi.org/10.3390/ijms20092359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539666/
https://www.ncbi.nlm.nih.gov/pubmed/31085998
http://dx.doi.org/10.3390/ijms20092359

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