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Inhibition of Calcium/Calmodulin-Dependent Protein Kinase Kinase β Is Detrimental in Hypoxia–Ischemia Neonatal Brain Injury

Neonatal hypoxia–ischemia (HI) is a major cause of death and disability in neonates. HI leads to a dramatic rise in intracellular calcium levels, which was originally thought to be detrimental to the brain. However, it has been increasingly recognized that this calcium signaling may also play an imp...

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Detalles Bibliográficos
Autores principales: Min, Jia-Wei, Bu, Fan, Qi, Li, Munshi, Yashasvee, Kim, Gab Seok, Marrelli, Sean P., McCullough, Louise D., Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539688/
https://www.ncbi.nlm.nih.gov/pubmed/31027360
http://dx.doi.org/10.3390/ijms20092063