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Modulation of SUR1 K(ATP) Channel Subunit Activity in the Peripheral Nervous System Reduces Mechanical Hyperalgesia after Nerve Injury in Mice
The ATP-sensitive K(+) channel (K(ATP)) is involved in hypersensitivity during chronic pain and is presumed to be a downstream target of mu opioid receptors. Multiple subtypes of K(ATP) channels exist in the peripheral and central nervous system and their activity may be inversely correlated to chro...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539735/ https://www.ncbi.nlm.nih.gov/pubmed/31067750 http://dx.doi.org/10.3390/ijms20092251 |