Cargando…

Evolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages

To appraise how evolutionary processes, such as gene duplication and loss, influence an organism’s xenobiotic sensitivity is a critical question in toxicology. Of particular importance are gene families involved in the mediation of detoxification responses, such as members of the nuclear receptor su...

Descripción completa

Detalles Bibliográficos
Autores principales: Fonseca, Elza S. S., Ruivo, Raquel, Machado, André M., Conrado, Francisca, Tay, Boon-Hui, Venkatesh, Byrappa, Santos, Miguel M., Castro, L. Filipe C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539745/
https://www.ncbi.nlm.nih.gov/pubmed/31083458
http://dx.doi.org/10.3390/ijms20092331