Synthesis and Anticancer Activity of Novel 9-O-Substituted Berberine Derivatives

Berberine is a bioactive isoquinoline alkaloid derived from many plants. Although berberine has been shown to inhibit growth and induce apoptosis of several tumor cell lines, its poor absorption and moderate activity hamper its full therapeutic potential. Here, we describe the synthesis of a series...

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Detalles Bibliográficos
Autores principales: Milata, Viktor, Svedova, Alexandra, Barbierikova, Zuzana, Holubkova, Eva, Cipakova, Ingrid, Cholujova, Dana, Jakubikova, Jana, Panik, Miroslav, Jantova, Sona, Brezova, Vlasta, Cipak, Lubos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539820/
https://www.ncbi.nlm.nih.gov/pubmed/31052469
http://dx.doi.org/10.3390/ijms20092169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539820/
https://www.ncbi.nlm.nih.gov/pubmed/31052469
http://dx.doi.org/10.3390/ijms20092169

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