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Synthesis and Anticancer Activity of Novel 9-O-Substituted Berberine Derivatives
Berberine is a bioactive isoquinoline alkaloid derived from many plants. Although berberine has been shown to inhibit growth and induce apoptosis of several tumor cell lines, its poor absorption and moderate activity hamper its full therapeutic potential. Here, we describe the synthesis of a series...
Autores principales: | Milata, Viktor, Svedova, Alexandra, Barbierikova, Zuzana, Holubkova, Eva, Cipakova, Ingrid, Cholujova, Dana, Jakubikova, Jana, Panik, Miroslav, Jantova, Sona, Brezova, Vlasta, Cipak, Lubos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539820/ https://www.ncbi.nlm.nih.gov/pubmed/31052469 http://dx.doi.org/10.3390/ijms20092169 |
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