How to Steer and Control ERK and the ERK Signaling Cascade Exemplified by Looking at Cardiac Insufficiency

Mathematical optimization framework allows the identification of certain nodes within a signaling network. In this work, we analyzed the complex extracellular-signal-regulated kinase 1 and 2 (ERK1/2) cascade in cardiomyocytes using the framework to find efficient adjustment screws for this cascade t...

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Detalles Bibliográficos
Autores principales: Breitenbach, Tim, Lorenz, Kristina, Dandekar, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539830/
https://www.ncbi.nlm.nih.gov/pubmed/31052520
http://dx.doi.org/10.3390/ijms20092179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539830/
https://www.ncbi.nlm.nih.gov/pubmed/31052520
http://dx.doi.org/10.3390/ijms20092179

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