PhSeZnCl in the Synthesis of Steroidal β-Hydroxy-Phenylselenides Having Antibacterial Activity

We report here the reaction of in situ prepared PhSeZnCl with steroid derivatives having an epoxide as an electrophilic functionalization. The corresponding ring-opening reaction resulted to be regio- and stereoselective affording to novel phenylselenium-substituted steroids. Assessment of their ant...

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Detalles Bibliográficos
Autores principales: Jastrzebska, Izabella, Mellea, Stefano, Salerno, Valerio, Grzes, Pawel Adam, Siergiejczyk, Leszek, Niemirowicz-Laskowska, Katarzyna, Bucki, Robert, Monti, Bonifacio, Santi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539910/
https://www.ncbi.nlm.nih.gov/pubmed/31032813
http://dx.doi.org/10.3390/ijms20092121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539910/
https://www.ncbi.nlm.nih.gov/pubmed/31032813
http://dx.doi.org/10.3390/ijms20092121

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