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PhSeZnCl in the Synthesis of Steroidal β-Hydroxy-Phenylselenides Having Antibacterial Activity
We report here the reaction of in situ prepared PhSeZnCl with steroid derivatives having an epoxide as an electrophilic functionalization. The corresponding ring-opening reaction resulted to be regio- and stereoselective affording to novel phenylselenium-substituted steroids. Assessment of their ant...
Autores principales: | Jastrzebska, Izabella, Mellea, Stefano, Salerno, Valerio, Grzes, Pawel Adam, Siergiejczyk, Leszek, Niemirowicz-Laskowska, Katarzyna, Bucki, Robert, Monti, Bonifacio, Santi, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539910/ https://www.ncbi.nlm.nih.gov/pubmed/31032813 http://dx.doi.org/10.3390/ijms20092121 |
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