Quantitative Structure–Activity Relationships for the Flavonoid-Mediated Inhibition of P-Glycoprotein in KB/MDR1 Cells

P-glycoprotein (P-gp) serves as a therapeutic target for the development of inhibitors to overcome multidrug resistance (MDR) in cancer cells. In order to enhance the uptake of chemotherapy drugs, larger amounts of P-gp inhibitors are required. Besides several chemically synthesized P-gp inhibitors,...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Mengmeng, Fang, Yajing, Cao, Weiwei, Liang, Fuqiang, Pan, Siyi, Xu, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539955/
https://www.ncbi.nlm.nih.gov/pubmed/31035631
http://dx.doi.org/10.3390/molecules24091661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539955/
https://www.ncbi.nlm.nih.gov/pubmed/31035631
http://dx.doi.org/10.3390/molecules24091661

Ejemplares similares