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Quantitative Structure–Activity Relationships for the Flavonoid-Mediated Inhibition of P-Glycoprotein in KB/MDR1 Cells

P-glycoprotein (P-gp) serves as a therapeutic target for the development of inhibitors to overcome multidrug resistance (MDR) in cancer cells. In order to enhance the uptake of chemotherapy drugs, larger amounts of P-gp inhibitors are required. Besides several chemically synthesized P-gp inhibitors,...

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Detalles Bibliográficos
Autores principales:	Xia, Mengmeng, Fang, Yajing, Cao, Weiwei, Liang, Fuqiang, Pan, Siyi, Xu, Xiaoyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539955/ https://www.ncbi.nlm.nih.gov/pubmed/31035631 http://dx.doi.org/10.3390/molecules24091661

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