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The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy

Background: Ischemia/reperfusion (I/R) caused by ischemic stroke treatments leads to brain injury, and autophagy plays a role in the pathology. Astragaloside IV is a potential neuroprotectant, but its underlying mechanism on cerebral I/R injury needs to be explored. The objective of this study is to...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Zhang, Ying, Jin, Xiao-fei, Zhou, Xiao-hong, Dong, Xian-hui, Yu, Wen-tao, Gao, Wei-juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539971/
https://www.ncbi.nlm.nih.gov/pubmed/31086091
http://dx.doi.org/10.3390/molecules24091838