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Down-Regulation of MHC Class I Expression in Human Keratinocytes Using Viral Vectors Containing US11 Gene of Human Cytomegalovirus and Cultivation on Bovine Collagen-Elastin Matrix (Matriderm(®)): Potential Approach for an Immune-Privileged Skin Substitute

Skin transplantation, especially in burn patients, is still challenging because surgeons are faced with limited disposability of autologous donor side material. The in vitro culture of keratinocytes has become an important reconstructive option. However, only non-immunogenic allogenic keratinocytes...

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Detalles Bibliográficos
Autores principales: Schlottmann, Frederik, Strauss, Sarah, Hake, Kevin, Vogt, Peter M., Bucan, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540026/
https://www.ncbi.nlm.nih.gov/pubmed/31027326
http://dx.doi.org/10.3390/ijms20092056