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Formulation of Nanomicelles to Improve the Solubility and the Oral Absorption of Silymarin

Two novel nanomicellar formulations were developed to improve the poor aqueous solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and mixed nanomicelles combining Soluplus with d-α-tocopherol polyethylene glycol 1000 succinate (vitamin E TPGS) were prepared usin...

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Detalles Bibliográficos
Autores principales: Piazzini, Vieri, D’Ambrosio, Mario, Luceri, Cristina, Cinci, Lorenzo, Landucci, Elisa, Bilia, Anna Rita, Bergonzi, Maria Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540123/
https://www.ncbi.nlm.nih.gov/pubmed/31052197
http://dx.doi.org/10.3390/molecules24091688