Cargando…

Formulation of Nanomicelles to Improve the Solubility and the Oral Absorption of Silymarin

Two novel nanomicellar formulations were developed to improve the poor aqueous solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and mixed nanomicelles combining Soluplus with d-α-tocopherol polyethylene glycol 1000 succinate (vitamin E TPGS) were prepared usin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Piazzini, Vieri, D’Ambrosio, Mario, Luceri, Cristina, Cinci, Lorenzo, Landucci, Elisa, Bilia, Anna Rita, Bergonzi, Maria Camilla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540123/ https://www.ncbi.nlm.nih.gov/pubmed/31052197 http://dx.doi.org/10.3390/molecules24091688

Ejemplares similares

Nanoemulsion for improving solubility and permeability of Vitex agnus-castus extract: formulation and in vitro evaluation using PAMPA and Caco-2 approaches
por: Piazzini, Vieri, et al.
Publicado: (2017)

Formulation of a Phenol-Rich Extract from Unripe Olives (Olea europaea L.) in Microemulsion to Improve Its Solubility and Intestinal Permeability
por: Cecchi, Lorenzo, et al.
Publicado: (2020)

Nanostructured Lipid Carriers Can Enhance Oral Absorption of Khellin, a Natural Pleiotropic Molecule
por: Vanti, Giulia, et al.
Publicado: (2021)

Stealth and Cationic Nanoliposomes as Drug Delivery Systems to Increase Andrographolide BBB Permeability
por: Piazzini, Vieri, et al.
Publicado: (2018)

Emergent Strategies for Natural Products Delivery
por: Bilia, Anna Rita, et al.
Publicado: (2020)

Stable, Monodisperse, and Highly Cell-Permeating Nanocochleates from Natural Soy Lecithin Liposomes
por: Asprea, Martina, et al.
Publicado: (2019)

Successful Brain Delivery of Andrographolide Loaded in Human Albumin Nanoparticles to TgCRND8 Mice, an Alzheimer’s Disease Mouse Model
por: Bilia, Anna Rita, et al.
Publicado: (2019)

Preparation of Liposomal Formulations for Ocular Delivery of Thymoquinone: In Vitro Evaluation in HCEC-2 e HConEC Cells
por: Landucci, Elisa, et al.
Publicado: (2021)

Enhanced Neuroprotective Effects of Panax ginseng G115(®) and Ginkgo biloba GK501(®) Combinations In Vitro Models of Excitotoxicity
por: Landucci, Elisa, et al.
Publicado: (2019)

Niosomal Formulation of a Lipoyl-Carnosine Derivative Targeting TRPA1 Channels in Brain
por: Maestrelli, Francesca, et al.
Publicado: (2019)

The Anti-Arthritic Efficacy of Khellin Loaded in Ascorbyl Decanoate Nanovesicles after an Intra-Articular Administration
por: Vanti, Giulia, et al.
Publicado: (2021)

Impact of Preoperative Immunonutrition on Oxidative Stress and Gut Barrier Function in Surgical Patients with Crohn’s Disease
por: Bigagli, Elisabetta, et al.
Publicado: (2023)

Pentacyclic Triterpenes from Olive Leaves Formulated in Microemulsion: Characterization and Role in De Novo Lipogenesis in HepG2 Cells
por: Vasarri, Marzia, et al.
Publicado: (2023)

New Oral Formulation and in Vitro Evaluation of Docetaxel-Loaded Nanomicelles
por: Hekmat, Atefeh, et al.
Publicado: (2016)

Evaluation and Comparison of Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) as Vectors to Develop Hydrochlorothiazide Effective and Safe Pediatric Oral Liquid Formulations
por: Mura, Paola, et al.
Publicado: (2021)

Hydrochlorothiazide Use and Risk of Nonmelanoma Skin Cancers: A Biological Plausibility Study
por: Bigagli, Elisabetta, et al.
Publicado: (2021)

Involvement of MIR-126 and MMP9 in the Pathogenesis of Intra-Abdominal Fistulizing Crohn’s Disease: A Brief Research Report
por: Luceri, Cristina, et al.
Publicado: (2022)

Solubility and Permeability Enhancement of Oleanolic Acid by Solid Dispersion in Poloxamers and γ-CD
por: De Stefani, Chiara, et al.
Publicado: (2022)

Novel nanomicelle formulation to enhance bioavailability and stability of curcuminoids
por: Hatamipour, Mahdi, et al.
Publicado: (2019)

A Comparative In Vitro Evaluation of the Anti-Inflammatory Effects of a Tisochrysis lutea Extract and Fucoxanthin
por: Bigagli, Elisabetta, et al.
Publicado: (2021)

Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis
por: Micheli, Laura, et al.
Publicado: (2019)

Thyroid Hormone, Thyroid Hormone Metabolites and Mast Cells: A Less Explored Issue
por: Landucci, Elisa, et al.
Publicado: (2019)

Formulation of Nanomicelles Loaded with Cannabidiol as a Platform for Neuroprotective Therapy
por: Yordanov, Yordan, et al.
Publicado: (2022)

Comparison of Chitosan Nanoparticles and Soluplus Micelles to Optimize the Bioactivity of Posidonia oceanica Extract on Human Neuroblastoma Cell Migration
por: Piazzini, Vieri, et al.
Publicado: (2019)

Modified mixed nanomicelles with collagen peptides enhanced oral absorption of Cucurbitacin B: preparation and evaluation
por: Tang, Lan, et al.
Publicado: (2018)

Therapeutic Effect of Polymeric Nanomicelles Formulation of LY2157299-Galunisertib on CCl(4)-Induced Liver Fibrosis in Rats
por: Panzarini, Elisa, et al.
Publicado: (2022)

Formulation and Characterization of Mupirocin Nanomicelles in Insulin-Based Gel for Dermatological Application
por: Zubairi, Maysaa B., et al.
Publicado: (2023)

Soluplus(®) polymeric nanomicelles improve solubility of BCS-class II drugs
por: Pignatello, Rosario, et al.
Publicado: (2022)

Essential Oil of Artemisia annua L.: An Extraordinary Component with Numerous Antimicrobial Properties
por: Bilia, Anna Rita, et al.
Publicado: (2014)

Formulation Strategies for Enhancing the Bioavailability of Silymarin: The State of the Art
por: Di Costanzo, Alfonso, et al.
Publicado: (2019)

Exosomes secreted from human colon cancer cells influence the adhesion of neighboring metastatic cells: Role of microRNA-210
por: Bigagli, Elisabetta, et al.
Publicado: (2016)

Antinociceptive Action of Thymoquinone-Loaded Liposomes in an In Vivo Model of Tendinopathy
por: Micheli, Laura, et al.
Publicado: (2023)

Intra-Articular Route for the System of Molecules 14G1862 from Centella asiatica: Pain Relieving and Protective Effects in a Rat Model of Osteoarthritis
por: Micheli, Laura, et al.
Publicado: (2020)

Low levels of miR-34c in nasal washings as a candidate marker of aggressive disease in wood and leather exposed workers with sinonasal intestinal-type adenocarcinomas (ITACs)
por: Bigagli, Elisabetta, et al.
Publicado: (2022)

Development and Percutaneous Permeation Study of Escinosomes, Escin-Based Nanovesicles Loaded with Berberine Chloride
por: Vanti, Giulia, et al.
Publicado: (2019)

Tisochrysis lutea F&M-M36 Mitigates Risk Factors of Metabolic Syndrome and Promotes Visceral Fat Browning through β3-Adrenergic Receptor/UCP1 Signaling
por: D’Ambrosio, Mario, et al.
Publicado: (2023)

Essential Oils Loaded in Nanosystems: A Developing Strategy for a Successful Therapeutic Approach
por: Bilia, Anna Rita, et al.
Publicado: (2014)

Co-Delivery of Berberine Chloride and Tariquidar in Nanoliposomes Enhanced Intracellular Berberine Chloride in a Doxorubicin-Resistant K562 Cell Line Due to P-gp Overexpression
por: Vanti, Giulia, et al.
Publicado: (2021)

Escinosomes: Safe and Successful Nanovesicles to Deliver Andrographolide by a Subcutaneous Route in a Mice Model of Oxaliplatin-Induced Neuropathy
por: Vanti, Giulia, et al.
Publicado: (2022)

Neuroprotective Effects of Thymoquinone by the Modulation of ER Stress and Apoptotic Pathway in In Vitro Model of Excitotoxicity
por: Landucci, Elisa, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0kh429dk39tp4obiqe6oqo9o6k