Phenotypic characterization of the novel, non-hotspot oncogenic KRAS mutants E31D and E63K

KRAS proto-oncogene, GTPase (KRAS) functions as a molecular switch at the apex of multiple signaling pathways controlling cell proliferation, differentiation, migration, and survival. Canonical KRAS mutants, such as those in codons 12 and 13, produce constitutively active oncoproteins that short-cir...

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Detalles Bibliográficos
Autores principales: Angeles, Arlou Kristina J., Yu, Ryan Timothy D., Cutiongco-De La Paz, Eva Maria, Garcia, Reynaldo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540134/
https://www.ncbi.nlm.nih.gov/pubmed/31289513
http://dx.doi.org/10.3892/ol.2019.10325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540134/
https://www.ncbi.nlm.nih.gov/pubmed/31289513
http://dx.doi.org/10.3892/ol.2019.10325

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