A Limonoid, 7-Deacetoxy-7-Oxogedunin (CG-1) from Andiroba (Carapa guianensis, Meliaceae) Lowers the Accumulation of Intracellular Lipids in Adipocytes via Suppression of IRS-1/Akt-Mediated Glucose Uptake and a Decrease in GLUT4 Expression

Limonoids are phytochemicals with a variety of biological properties. In the present study, we elucidated the molecular mechanism of suppression of adipogenesis in adipocytes by a limonoid, 7-deacetoxy-7-oxogedunin (CG-1) from Carapa guianensis (Meliaceae), known as andiroba. CG-1 reduced the accumu...

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Detalles Bibliográficos
Autores principales: Matsumoto, Chihiro, Koike, Atsushi, Tanaka, Reiko, Fujimori, Ko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540142/
https://www.ncbi.nlm.nih.gov/pubmed/31035366
http://dx.doi.org/10.3390/molecules24091668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540142/
https://www.ncbi.nlm.nih.gov/pubmed/31035366
http://dx.doi.org/10.3390/molecules24091668

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