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Menaquinone-4 Suppresses Lipopolysaccharide-Induced Inflammation in MG6 Mouse Microglia-Derived Cells by Inhibiting the NF-κB Signaling Pathway

The overactivation of microglia is known to trigger inflammatory reactions in the central nervous system, which ultimately induce neuroinflammatory disorders including Alzheimer’s disease. However, increasing evidence has shown that menaquinone-4 (MK-4), a subtype of vitamin K(2), can attenuate infl...

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Detalles Bibliográficos
Autores principales: Saputra, Wahyu Dwi, Aoyama, Nao, Komai, Michio, Shirakawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540242/
https://www.ncbi.nlm.nih.gov/pubmed/31083359
http://dx.doi.org/10.3390/ijms20092317