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Fructose-1,6-Bisphosphate Protects Hippocampal Rat Slices from NMDA Excitotoxicity

Effects of fructose 1,6-bisphosphate (F-1,6-P2) towards N-methyl-d-aspartate NMDA excitotoxicity were evaluated in rat organotypic hippocampal brain slice cultures (OHSC) challenged for 3 h with 30 μM NMDA, followed by incubations (24, 48, and 72 h) without (controls) and with F-1,6-P2 (0.5, 1 or 1....

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Detalles Bibliográficos
Autores principales: Yakoub, Kamal M., Lazzarino, Giacomo, Amorini, Angela M., Caruso, Giuseppe, Scazzone, Concetta, Ciaccio, Marcello, Tavazzi, Barbara, Lazzarino, Giuseppe, Belli, Antonio, Di Pietro, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540300/
https://www.ncbi.nlm.nih.gov/pubmed/31067671
http://dx.doi.org/10.3390/ijms20092239