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Stochastic modelling of tyrosine kinase inhibitor rotation therapy in chronic myeloid leukaemia

BACKGROUND: Resistance towards targeted cancer treatments caused by single nucleotide variations is a major issue in many malignancies. Currently, there are a number of available drugs for chronic myeloid leukaemia (CML), which are overcome by different sets of mutations. The main aim of this study...

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Detalles Bibliográficos
Autores principales: Lindström, H. Jonathan G., de Wijn, Astrid S., Friedman, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540367/
https://www.ncbi.nlm.nih.gov/pubmed/31138173
http://dx.doi.org/10.1186/s12885-019-5690-5