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Stochastic modelling of tyrosine kinase inhibitor rotation therapy in chronic myeloid leukaemia
BACKGROUND: Resistance towards targeted cancer treatments caused by single nucleotide variations is a major issue in many malignancies. Currently, there are a number of available drugs for chronic myeloid leukaemia (CML), which are overcome by different sets of mutations. The main aim of this study...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540367/ https://www.ncbi.nlm.nih.gov/pubmed/31138173 http://dx.doi.org/10.1186/s12885-019-5690-5 |