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Downregulation of α7 nicotinic acetylcholine receptors in peripheral blood monocytes is associated with enhanced inflammation in preeclampsia

BACKGROUND: Preeclampsia is associated with chronic inflammation. The cholinergic anti-inflammatory pathway regulates systemic inflammation through activating α7 nicotinic acetylcholine receptors (α7nAChR) expressed in monocytes/macrophages. This study aimed to investigate the role of α7nAChR in per...

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Detalles Bibliográficos
Autores principales: Xu, Hongmei, Shi, Qingyang, Mo, Yanxiang, Wu, Linlin, Gu, Jishuang, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540389/
https://www.ncbi.nlm.nih.gov/pubmed/31138166
http://dx.doi.org/10.1186/s12884-019-2340-5