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Placenta-specific 8 is a potential novel target for osimertinib resistance in non-small cell lung cancer

Currently, osimertinib (AZD9291) is the only third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor approved by the Food and Drug Administration for the treatment of non-small cell lung cancer (NSCLC) with EGFR T790M mutations. However, acquired resistance is an inevitabl...

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Detalles Bibliográficos
Autores principales: Fei, Xiaoyun, Wang, Gang, Shen, Hui, Gu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540393/
https://www.ncbi.nlm.nih.gov/pubmed/31289574
http://dx.doi.org/10.3892/ol.2019.10344