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Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson’s disease models

BACKGROUND: Mutants which carry mutations in genes encoding mitochondrial ligases MUL1 and PARKIN are convenient Drosophila models of Parkinson’s disease (PD). In several studies it has been shown that in Parkinson’s disease sleep disturbance occurs, which may be the result of a disturbed circadian...

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Detalles Bibliográficos
Autores principales: Doktór, Bartosz, Damulewicz, Milena, Pyza, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415/
https://www.ncbi.nlm.nih.gov/pubmed/31138137
http://dx.doi.org/10.1186/s12868-019-0506-8