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CKD-602, a topoisomerase I inhibitor, induces apoptosis and cell-cycle arrest and inhibits invasion in cervical cancer

BACKGROUND: Cervical cancer is the third most common gynecological malignancy. Conventional treatment options are known to be ineffective for the majority of patients with advanced or recurrent cervical cancer. Therefore, novel therapeutic agents for cervical cancer are necessary. In this study, the...

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Detalles Bibliográficos
Autores principales: Lee, Sungha, Ho, Jung Yoon, Liu, Jing Jing, Lee, Hyewon, Park, Jae Young, Baik, Minwha, Ko, Minji, Lee, Seon Ui, Choi, Youn Jin, Hur, Soo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540464/
https://www.ncbi.nlm.nih.gov/pubmed/31138113
http://dx.doi.org/10.1186/s10020-019-0089-y