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TelomereHunter – in silico estimation of telomere content and composition from cancer genomes

BACKGROUND: Establishment of telomere maintenance mechanisms is a universal step in tumor development to achieve replicative immortality. These processes leave molecular footprints in cancer genomes in the form of altered telomere content and aberrations in telomere composition. To retrieve these te...

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Detalles Bibliográficos
Autores principales: Feuerbach, Lars, Sieverling, Lina, Deeg, Katharina I., Ginsbach, Philip, Hutter, Barbara, Buchhalter, Ivo, Northcott, Paul A., Mughal, Sadaf S., Chudasama, Priya, Glimm, Hanno, Scholl, Claudia, Lichter, Peter, Fröhling, Stefan, Pfister, Stefan M., Jones, David T. W., Rippe, Karsten, Brors, Benedikt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540518/
https://www.ncbi.nlm.nih.gov/pubmed/31138115
http://dx.doi.org/10.1186/s12859-019-2851-0