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TelomereHunter – in silico estimation of telomere content and composition from cancer genomes
BACKGROUND: Establishment of telomere maintenance mechanisms is a universal step in tumor development to achieve replicative immortality. These processes leave molecular footprints in cancer genomes in the form of altered telomere content and aberrations in telomere composition. To retrieve these te...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540518/ https://www.ncbi.nlm.nih.gov/pubmed/31138115 http://dx.doi.org/10.1186/s12859-019-2851-0 |