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Pressure overload induced right ventricular remodeling is not attenuated by the anti-fibrotic agent pirfenidone
Cardiac fibrosis contributes to the development of heart failure in pulmonary hypertension. We aimed to assess the development of fibrosis and the effects of treatment with the anti-fibrotic agent pirfenidone in pressure overload induced right ventricular (RV) failure. Wistar rat weanlings were rand...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540527/ https://www.ncbi.nlm.nih.gov/pubmed/30997866 http://dx.doi.org/10.1177/2045894019848659 |