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Pressure overload induced right ventricular remodeling is not attenuated by the anti-fibrotic agent pirfenidone

Cardiac fibrosis contributes to the development of heart failure in pulmonary hypertension. We aimed to assess the development of fibrosis and the effects of treatment with the anti-fibrotic agent pirfenidone in pressure overload induced right ventricular (RV) failure. Wistar rat weanlings were rand...

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Detalles Bibliográficos
Autores principales:	Andersen, Stine, Birkmose Axelsen, Julie, Ringgaard, Steffen, Randel Nyengaard, Jens, Holm Nielsen, Signe, Genovese, Federica, Asser Karsdal, Morten, Adler Hyldebrandt, Janus, Brandt Sørensen, Charlotte, de Man, Frances S., Jan Bogaard, Harm, Erik Nielsen-Kudsk, Jens, Andersen, Asger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540527/ https://www.ncbi.nlm.nih.gov/pubmed/30997866 http://dx.doi.org/10.1177/2045894019848659

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