Rosiglitazone promotes ENaC-mediated alveolar fluid clearance in acute lung injury through the PPARγ/SGK1 signaling pathway

BACKGROUND: Pulmonary edema is one of the pathological characteristics of acute respiratory distress syndrome (ARDS). The epithelial sodium channel (ENaC) is thought to be the rate-limiting factor for alveolar fluid clearance (AFC) during pulmonary edema. The peroxisome proliferator-activated recept...

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Detalles Bibliográficos
Autores principales: He, Jing, Qi, Di, Tang, Xu-mao, Deng, Wang, Deng, Xin-yu, Zhao, Yan, Wang, Dao-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540532/
https://www.ncbi.nlm.nih.gov/pubmed/31160894
http://dx.doi.org/10.1186/s11658-019-0154-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540532/
https://www.ncbi.nlm.nih.gov/pubmed/31160894
http://dx.doi.org/10.1186/s11658-019-0154-0

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