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Rosiglitazone promotes ENaC-mediated alveolar fluid clearance in acute lung injury through the PPARγ/SGK1 signaling pathway

BACKGROUND: Pulmonary edema is one of the pathological characteristics of acute respiratory distress syndrome (ARDS). The epithelial sodium channel (ENaC) is thought to be the rate-limiting factor for alveolar fluid clearance (AFC) during pulmonary edema. The peroxisome proliferator-activated recept...

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Detalles Bibliográficos
Autores principales:	He, Jing, Qi, Di, Tang, Xu-mao, Deng, Wang, Deng, Xin-yu, Zhao, Yan, Wang, Dao-xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540532/ https://www.ncbi.nlm.nih.gov/pubmed/31160894 http://dx.doi.org/10.1186/s11658-019-0154-0

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