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Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro

BACKGROUND: Tumor-associated macrophages (TAM) are expanded and exhibit tumor-promoting properties within the tumor microenvironment. Current methods to study TAM have not been replicated across cancer types and often do not include exogenous growth factors from the tumor, a key factor in TAM differ...

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Detalles Bibliográficos
Autores principales: Benner, Brooke, Scarberry, Luke, Suarez-Kelly, Lorena P., Duggan, Megan C., Campbell, Amanda R., Smith, Emily, Lapurga, Gabriella, Jiang, Kallie, Butchar, Jonathan P., Tridandapani, Susheela, Howard, John Harrison, Baiocchi, Robert A., Mace, Thomas A., Carson, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540573/
https://www.ncbi.nlm.nih.gov/pubmed/31138333
http://dx.doi.org/10.1186/s40425-019-0622-0