Rationale for Targeting Deregulated Metabolic Pathways as a Therapeutic Strategy in Acute Myeloid Leukemia

Metabolic reprogramming is a common cancer cell phenotype as it sustains growth and proliferation. Targeting metabolic activities offers a wide range of therapeutic possibilities which are applicable to acute myeloid leukemia (AML). Indeed, in addition to the IDH1/2-mutated AML model which establish...

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Detalles Bibliográficos
Autores principales: Chapuis, Nicolas, Poulain, Laury, Birsen, Rudy, Tamburini, Jerome, Bouscary, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540604/
https://www.ncbi.nlm.nih.gov/pubmed/31192118
http://dx.doi.org/10.3389/fonc.2019.00405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540604/
https://www.ncbi.nlm.nih.gov/pubmed/31192118
http://dx.doi.org/10.3389/fonc.2019.00405

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