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Rationale for Targeting Deregulated Metabolic Pathways as a Therapeutic Strategy in Acute Myeloid Leukemia
Metabolic reprogramming is a common cancer cell phenotype as it sustains growth and proliferation. Targeting metabolic activities offers a wide range of therapeutic possibilities which are applicable to acute myeloid leukemia (AML). Indeed, in addition to the IDH1/2-mutated AML model which establish...
Autores principales: | Chapuis, Nicolas, Poulain, Laury, Birsen, Rudy, Tamburini, Jerome, Bouscary, Didier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540604/ https://www.ncbi.nlm.nih.gov/pubmed/31192118 http://dx.doi.org/10.3389/fonc.2019.00405 |
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