Emodin Rescues Intrahepatic Cholestasis via Stimulating FXR/BSEP Pathway in Promoting the Canalicular Export of Accumulated Bile

AIM: Bile salt export pump (BSEP) have been confirmed to play an important role for bile acid canalicular export in the treatment of cholestasis. In this study, we investigated the stimulatory effect of emodin on BSEP signaling pathway in cholestasis. METHODS: Cell and animal experiments were given...

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Detalles Bibliográficos
Autores principales: Xiong, Xiao-Li, Ding, Yan, Chen, Zhi-Lin, Wang, Yao, Liu, Pan, Qin, Huan, Zhou, Li-Shan, Zhang, Ling-Ling, Huang, Juan, Zhao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540617/
https://www.ncbi.nlm.nih.gov/pubmed/31191298
http://dx.doi.org/10.3389/fphar.2019.00522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540617/
https://www.ncbi.nlm.nih.gov/pubmed/31191298
http://dx.doi.org/10.3389/fphar.2019.00522

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