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Monitoring Patient Response to Pembrolizumab With Peripheral Blood Exhaustion Marker Profiles
Exhausted T cells are effector T cells that are silenced due to continuous T cell receptor (TCR) stimulation from persistent antigens. Characteristics of exhaustion include the increased expression of multiple inhibitory receptors such as programme death-1[PD-1], lymphocyte activation gene 3 [LAG-3]...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540682/ https://www.ncbi.nlm.nih.gov/pubmed/31192212 http://dx.doi.org/10.3389/fmed.2019.00113 |