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Monitoring Patient Response to Pembrolizumab With Peripheral Blood Exhaustion Marker Profiles

Exhausted T cells are effector T cells that are silenced due to continuous T cell receptor (TCR) stimulation from persistent antigens. Characteristics of exhaustion include the increased expression of multiple inhibitory receptors such as programme death-1[PD-1], lymphocyte activation gene 3 [LAG-3]...

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Detalles Bibliográficos
Autores principales: Graves, Moira, CelliMarchett, Giovana, van Zyl, Belinda, Tang, Denise, Vilain, Ricardo E., van der Westhuizen, Andre, Bowden, Nikola A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540682/
https://www.ncbi.nlm.nih.gov/pubmed/31192212
http://dx.doi.org/10.3389/fmed.2019.00113