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The Role of 5-ALA in Low-Grade Gliomas and the Influence of Antiepileptic Drugs on Intraoperative Fluorescence

Objectives: Intraoperative tumor visualization with 5-aminolevulinic acid (5-ALA) induced protoporphyrin IX (PpIX) fluorescence is widely applied for improved resection of high-grade gliomas. However, visible fluorescence is present only in a minority of low-grade gliomas (LGGs) according to current...

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Detalles Bibliográficos
Autores principales: Goryaynov, Sergey A., Widhalm, Georg, Goldberg, Maria F., Chelushkin, Danil, Spallone, Aldo, Chernyshov, Kosta A., Ryzhova, Marina, Pavlova, Galina, Revischin, Alexander, Shishkina, Ludmila, Jukov, Vadim, Savelieva, Tatyana, Victor, Loschenov, Potapov, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540822/
https://www.ncbi.nlm.nih.gov/pubmed/31192128
http://dx.doi.org/10.3389/fonc.2019.00423